A mechanism for cell motility by active polar gels.
نویسندگان
چکیده
We analyse a generic motility model, with the motility mechanism arising by contractile stress due to the interaction of myosin and actin. A hydrodynamic active polar gel theory is used to model the cytoplasm of a cell and is combined with a Helfrich-type model to account for membrane properties. The overall model allows consideration of the motility without the necessity for local adhesion. Besides a detailed numerical approach together with convergence studies for the highly nonlinear free boundary problem, we also compare the induced flow field of the motile cell with that of classical squirmer models and identify the motile cell as a puller or pusher, depending on the strength of the myosin-actin interactions.
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ورودعنوان ژورنال:
- Journal of the Royal Society, Interface
دوره 12 107 شماره
صفحات -
تاریخ انتشار 2015